K22E (p.Lys22Glu) variant of HCN4 (Q9Y3Q4)
K22E (p.Lys22Glu) in HCN4 (Q9Y3Q4) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.45 / 1. The record also includes population frequency data and structural context.
K22E (p.Lys22Glu) variant details
- p.Lys22Glu
- Ensembl rs1595837744
- Missense
- Variant Prioritization Score for Impact Estimate 0.453
- REVEL 0.34
- MetaLR 0.82
- MetaSVM 0.58
- CADD 23.40
- PolyPhen-2 0.35
- SIFT 0.00
- Population evidence available
- Structural context available