K10R (p.Lys10Arg) variant of HCN4 (Q9Y3Q4)
K10R (p.Lys10Arg) in HCN4 (Q9Y3Q4) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.50 / 1. The record also includes population frequency data and structural context.
K10R (p.Lys10Arg) variant details
- p.Lys10Arg
- Ensembl rs2151228793
- Missense
- Variant Prioritization Score for Impact Estimate 0.504
- REVEL 0.42
- MetaLR 0.84
- MetaSVM 0.91
- CADD 23.10
- PolyPhen-2 0.08
- SIFT 0.00
- Population evidence available
- Structural context available