G63S (p.Gly63Ser) variant of HCN4 (Q9Y3Q4)
G63S (p.Gly63Ser) in HCN4 (Q9Y3Q4) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.32 / 1. The record also includes population frequency data and structural context.
G63S (p.Gly63Ser) variant details
- p.Gly63Ser
- gnomAD rs1319902889
- Missense
- Variant Prioritization Score for Impact Estimate 0.317
- REVEL 0.18
- MetaLR 0.75
- MetaSVM 0.25
- CADD 12.30
- PolyPhen-2 0.05
- SIFT 0.02
- Most common in the Non-Finnish European population (allele frequency 9.5e-07)
- Structural context available