G20R (p.Gly20Arg) variant of HCN4 (Q9Y3Q4)
G20R (p.Gly20Arg) in HCN4 (Q9Y3Q4) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.75 / 1. The record also includes population frequency data and structural context.
G20R (p.Gly20Arg) variant details
- p.Gly20Arg
- gnomAD rs868149827
- Missense
- Variant Prioritization Score for Impact Estimate 0.752
- REVEL 0.69
- MetaLR 0.97
- MetaSVM 1.10
- CADD 26.20
- PolyPhen-2 0.97
- SIFT 0.01
- Population evidence available
- Structural context available