E35G (p.Glu35Gly) variant of HCN4 (Q9Y3Q4)
E35G (p.Glu35Gly) in HCN4 (Q9Y3Q4) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.44 / 1. The record also includes population frequency data and structural context.
E35G (p.Glu35Gly) variant details
- p.Glu35Gly
- Ensembl rs2151228751
- Missense
- Variant Prioritization Score for Impact Estimate 0.444
- REVEL 0.31
- MetaLR 0.76
- MetaSVM 0.27
- CADD 22.30
- PolyPhen-2 0.00
- SIFT 0.14
- Population evidence available
- Structural context available