P109L (p.Pro109Leu) variant of GNA13 (Q14344)
P109L (p.Pro109Leu) in GNA13 (Q14344) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.74 / 1. The record also includes population frequency data.
P109L (p.Pro109Leu) variant details
- p.Pro109Leu
- ESP rs377750035
- TOPMed rs377750035
- Missense
- Variant Prioritization Score for Impact Estimate 0.741
- REVEL 0.66
- MetaLR 0.84
- MetaSVM 0.72
- CADD 28.90
- PolyPhen-2 1.00
- SIFT 0.01
- Most common in the Non-Finnish European population (allele frequency 9e-07)