C53F (p.Cys53Phe) variant of GJB1 (Gap junction beta-1 protein)

C53F (p.Cys53Phe) in GJB1 (Gap junction beta-1 protein) is a missense change. Clinical records from ClinVar, EBI, and UniProt describe it as uncertain significance in the context of Charcot-Marie-Tooth Neuropathy X. The record also includes published literature and structural context.

C53F (p.Cys53Phe) variant details