L10F (p.Leu10Phe) variant of GATA6 (Transcription factor GATA-6)
L10F (p.Leu10Phe) in GATA6 (Transcription factor GATA-6) is a missense change. Clinical records from UniProt describe it as variant assessed as somatic; high impact. The available variant effect predictions contribute to a CATVariant prioritization score of 0.43 / 1. The record also includes population frequency data and structural context.
L10F (p.Leu10Phe) variant details
- p.Leu10Phe
- NCI-TCGA TCGA novel
- Variant assessed as somatic; high impact.
- Missense
- Variant Prioritization Score for Impact Estimate 0.429
- REVEL 0.40
- CADD 22.60
- PolyPhen-2 0.16
- SIFT 0.00
- UniProt: Variant assessed as somatic; high impact.
- Population evidence available
- Structural context available