Y35* (p.Tyr35Ter) variant of GATA3 (P23771)
Y35* (p.Tyr35Ter) in GATA3 (P23771) is a protein-truncating change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.59 / 1. The record also includes population frequency data, published literature, and structural context.
Y35* (p.Tyr35Ter) variant details
- p.Tyr35Ter
- gnomAD 10-8055760-C-A
- Stop Gained
- Variant Prioritization Score for Impact Estimate 0.593
- AlphaMissense 0.81
- MetaLR 0.54
- MetaSVM -0.03
- CADD 36.00
- PolyPhen-2 0.92
- SIFT 0.00
- Population evidence available
- Structural context available
- Literature evidence available