W10L (p.Trp10Leu) variant of GATA3 (P23771)
W10L (p.Trp10Leu) in GATA3 (P23771) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.83 / 1. The record also includes population frequency data, published literature, and structural context.
W10L (p.Trp10Leu) variant details
- p.Trp10Leu
- gnomAD 10-8055684-G-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.83
- REVEL 0.83
- MetaLR 0.93
- MetaSVM 0.93
- CADD 28.00
- PolyPhen-2 0.37
- SIFT 0.00
- Population evidence available
- Structural context available
- Literature evidence available