W10C (p.Trp10Cys) variant of GATA3 (P23771)
W10C (p.Trp10Cys) in GATA3 (P23771) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.90 / 1. The record also includes population frequency data, published literature, and structural context.
W10C (p.Trp10Cys) variant details
- p.Trp10Cys
- gnomAD 10-8055685-G-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.897
- REVEL 0.92
- MetaLR 0.97
- MetaSVM 1.10
- CADD 33.00
- PolyPhen-2 0.94
- SIFT 0.00
- Population evidence available
- Structural context available
- Literature evidence available