G21W (p.Gly21Trp) variant of GATA3 (P23771)
G21W (p.Gly21Trp) in GATA3 (P23771) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.81 / 1. The record also includes population frequency data, published literature, and structural context.
G21W (p.Gly21Trp) variant details
- p.Gly21Trp
- gnomAD 10-8055716-G-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.805
- REVEL 0.75
- MetaLR 0.93
- MetaSVM 1.03
- CADD 32.00
- PolyPhen-2 0.95
- SIFT 0.00
- Population evidence available
- Structural context available
- Literature evidence available