G21V (p.Gly21Val) variant of GATA3 (P23771)
G21V (p.Gly21Val) in GATA3 (P23771) is a missense change. Clinical records from UniProt describe it as variant assessed as somatic; moderate impact. The available variant effect predictions contribute to a CATVariant prioritization score of 0.73 / 1. The record also includes population frequency data and structural context.
G21V (p.Gly21Val) variant details
- p.Gly21Val
- NCI-TCGA TCGA novel
- Variant assessed as somatic; moderate impact.
- Missense
- Variant Prioritization Score for Impact Estimate 0.733
- REVEL 0.66
- MetaLR 0.90
- MetaSVM 0.96
- CADD 24.90
- PolyPhen-2 0.46
- SIFT 0.08
- UniProt: Variant assessed as somatic; moderate impact.
- Population evidence available
- Structural context available