D25G (p.Asp25Gly) variant of GATA3 (P23771)
D25G (p.Asp25Gly) in GATA3 (P23771) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.48 / 1. The record also includes population frequency data and structural context.
D25G (p.Asp25Gly) variant details
- p.Asp25Gly
- gnomAD rs1469106968
- Missense
- Variant Prioritization Score for Impact Estimate 0.479
- REVEL 0.36
- MetaLR 0.73
- MetaSVM 0.25
- CADD 23.50
- PolyPhen-2 0.02
- SIFT 0.16
- Most common in the Latino/Admixed American population (allele frequency 2.6e-05)
- Structural context available