T16I (p.Thr16Ile) variant of G6PC1 (P35575)
T16I (p.Thr16Ile) in G6PC1 (P35575) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.36 / 1. The record also includes population frequency data, published literature, and structural context.
T16I (p.Thr16Ile) variant details
- p.Thr16Ile
- gnomAD 17-42900923-C-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.359
- REVEL 0.22
- MetaLR 0.13
- MetaSVM -0.90
- CADD 16.50
- PolyPhen-2 0.11
- SIFT 0.62
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available
- Literature evidence available