L168F (p.Leu168Phe) variant of FOXP3 (Forkhead box protein P3)
L168F (p.Leu168Phe) in FOXP3 (Forkhead box protein P3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.42 / 1. The record also includes population frequency data.
L168F (p.Leu168Phe) variant details
- p.Leu168Phe
- TOPMed rs2066077912
- Missense
- Variant Prioritization Score for Impact Estimate 0.425
- REVEL 0.44
- CADD 23.10
- PolyPhen-2 1.00
- SIFT 0.00
- Most common in the African/African-American population (allele frequency 3.8e-05)