G37E (p.Gly37Glu) variant of FOXP3 (Forkhead box protein P3)
G37E (p.Gly37Glu) in FOXP3 (Forkhead box protein P3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.42 / 1. The record also includes population frequency data and structural context.
G37E (p.Gly37Glu) variant details
- p.Gly37Glu
- TOPMed rs1194116356
- gnomAD rs1194116356
- Missense
- Variant Prioritization Score for Impact Estimate 0.422
- REVEL 0.48
- CADD 17.10
- PolyPhen-2 0.55
- SIFT 0.05
- Most common in the South Asian population (allele frequency 2e-05)
- Structural context available