W33L (p.Trp33Leu) variant of FOXO3 (Forkhead box protein O3)
W33L (p.Trp33Leu) in FOXO3 (Forkhead box protein O3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.70 / 1. The record also includes population frequency data, published literature, and structural context.
W33L (p.Trp33Leu) variant details
- p.Trp33Leu
- gnomAD 6-108561306-G-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.703
- REVEL 0.66
- MetaLR 0.82
- MetaSVM 0.87
- CADD 25.10
- PolyPhen-2 0.11
- SIFT 0.00
- Population evidence available
- Structural context available
- Literature evidence available