T32M (p.Thr32Met) variant of FOXO3 (Forkhead box protein O3)
T32M (p.Thr32Met) in FOXO3 (Forkhead box protein O3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.74 / 1. The record also includes population frequency data, published literature, and structural context.
T32M (p.Thr32Met) variant details
- p.Thr32Met
- gnomAD 6-108561303-C-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.741
- REVEL 0.70
- MetaLR 0.88
- MetaSVM 0.94
- CADD 25.80
- PolyPhen-2 0.76
- SIFT 0.00
- Population evidence available
- Structural context available
- Literature evidence available