S7A (p.Ser7Ala) variant of FOXO3 (Forkhead box protein O3)
S7A (p.Ser7Ala) in FOXO3 (Forkhead box protein O3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.37 / 1. The record also includes population frequency data and structural context.
S7A (p.Ser7Ala) variant details
- p.Ser7Ala
- Ensembl rs1562223603
- Missense
- Variant Prioritization Score for Impact Estimate 0.366
- REVEL 0.26
- MetaLR 0.30
- MetaSVM -0.76
- CADD 18.00
- PolyPhen-2 0.00
- SIFT 0.43
- Most common in the South Asian population (allele frequency 1.3e-05)
- Structural context available