S43T (p.Ser43Thr) variant of FOXO3 (Forkhead box protein O3)
S43T (p.Ser43Thr) in FOXO3 (Forkhead box protein O3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.43 / 1. The record also includes population frequency data, published literature, and structural context.
S43T (p.Ser43Thr) variant details
- p.Ser43Thr
- gnomAD 6-108561336-G-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.429
- REVEL 0.27
- MetaLR 0.44
- MetaSVM -0.21
- CADD 22.50
- PolyPhen-2 0.04
- SIFT 0.06
- Population evidence available
- Structural context available
- Literature evidence available