S43N (p.Ser43Asn) variant of FOXO3 (Forkhead box protein O3)
S43N (p.Ser43Asn) in FOXO3 (Forkhead box protein O3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.38 / 1. The record also includes population frequency data, published literature, and structural context.
S43N (p.Ser43Asn) variant details
- p.Ser43Asn
- gnomAD 6-108561336-G-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.382
- REVEL 0.19
- MetaLR 0.47
- MetaSVM -0.19
- CADD 17.20
- PolyPhen-2 0.00
- SIFT 0.26
- Population evidence available
- Structural context available
- Literature evidence available