S30F (p.Ser30Phe) variant of FOXO3 (Forkhead box protein O3)
S30F (p.Ser30Phe) in FOXO3 (Forkhead box protein O3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.70 / 1. The record also includes population frequency data and structural context.
S30F (p.Ser30Phe) variant details
- p.Ser30Phe
- TOPMed rs1276237221
- Missense
- Variant Prioritization Score for Impact Estimate 0.703
- REVEL 0.66
- MetaLR 0.78
- MetaSVM 0.75
- CADD 25.10
- PolyPhen-2 0.50
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 9.2e-07)
- Structural context available