S26R (p.Ser26Arg) variant of FOXO3 (Forkhead box protein O3)
S26R (p.Ser26Arg) in FOXO3 (Forkhead box protein O3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.35 / 1. The record also includes population frequency data, published literature, and structural context.
S26R (p.Ser26Arg) variant details
- p.Ser26Arg
- gnomAD 6-108561286-C-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.352
- REVEL 0.33
- MetaLR 0.46
- MetaSVM -0.24
- CADD 20.20
- PolyPhen-2 0.07
- SIFT 0.06
- Population evidence available
- Structural context available
- Literature evidence available