S12S (p.Ser12Ser) variant of FOXO3 (Forkhead box protein O3)
S12S (p.Ser12Ser) in FOXO3 (Forkhead box protein O3) is a synonymous change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.63 / 1. The record also includes population frequency data, published literature, and structural context.
S12S (p.Ser12Ser) variant details
- p.Ser12Ser
- rs925027831
- gnomAD 6-108561244-T-C
- Synonymous
- Variant Prioritization Score for Impact Estimate 0.633
- CADD 14.70
- Most common in the Non-Finnish European population (allele frequency 9.2e-07)
- Structural context available
- Literature evidence available