R27H (p.Arg27His) variant of FOXO3 (Forkhead box protein O3)
R27H (p.Arg27His) in FOXO3 (Forkhead box protein O3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.59 / 1. The record also includes population frequency data, published literature, and structural context.
R27H (p.Arg27His) variant details
- p.Arg27His
- gnomAD 6-108561288-G-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.587
- REVEL 0.50
- MetaLR 0.71
- MetaSVM 0.33
- CADD 24.50
- PolyPhen-2 0.00
- SIFT 0.00
- Population evidence available
- Structural context available
- Literature evidence available