Q41R (p.Gln41Arg) variant of FOXO3 (Forkhead box protein O3)
Q41R (p.Gln41Arg) in FOXO3 (Forkhead box protein O3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.33 / 1. The record also includes population frequency data and structural context.
Q41R (p.Gln41Arg) variant details
- p.Gln41Arg
- TOPMed rs1402941576
- gnomAD rs1402941576
- Missense
- Variant Prioritization Score for Impact Estimate 0.33
- REVEL 0.18
- MetaLR 0.36
- MetaSVM -0.63
- CADD 18.90
- PolyPhen-2 0.00
- SIFT 0.53
- Most common in the Non-Finnish European population (allele frequency 1.5e-05)
- Structural context available