Q41K (p.Gln41Lys) variant of FOXO3 (Forkhead box protein O3)
Q41K (p.Gln41Lys) in FOXO3 (Forkhead box protein O3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.35 / 1. The record also includes population frequency data and structural context.
Q41K (p.Gln41Lys) variant details
- p.Gln41Lys
- gnomAD rs1775777589
- Missense
- Variant Prioritization Score for Impact Estimate 0.352
- REVEL 0.22
- MetaLR 0.32
- MetaSVM -0.70
- CADD 16.90
- PolyPhen-2 0.00
- SIFT 0.91
- Most common in the African/African-American population (allele frequency 2.4e-05)
- Structural context available