Q25H (p.Gln25His) variant of FOXO3 (Forkhead box protein O3)
Q25H (p.Gln25His) in FOXO3 (Forkhead box protein O3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.43 / 1. The record also includes population frequency data and structural context.
Q25H (p.Gln25His) variant details
- p.Gln25His
- ExAC rs773001047
- TOPMed rs773001047
- gnomAD rs773001047
- Missense
- Variant Prioritization Score for Impact Estimate 0.433
- REVEL 0.41
- MetaLR 0.60
- MetaSVM 0.08
- CADD 23.90
- PolyPhen-2 0.46
- SIFT 0.06
- Most common in the Finnish in Finland (FIN) population (allele frequency 0.012)
- Structural context available