P8Q (p.Pro8Gln) variant of FOXO3 (Forkhead box protein O3)
P8Q (p.Pro8Gln) in FOXO3 (Forkhead box protein O3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.45 / 1. The record also includes population frequency data, published literature, and structural context.
P8Q (p.Pro8Gln) variant details
- p.Pro8Gln
- gnomAD 6-108561231-C-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.453
- REVEL 0.38
- MetaLR 0.40
- MetaSVM -0.24
- CADD 20.90
- PolyPhen-2 0.30
- SIFT 0.03
- Population evidence available
- Structural context available
- Literature evidence available