P8L (p.Pro8Leu) variant of FOXO3 (Forkhead box protein O3)
P8L (p.Pro8Leu) in FOXO3 (Forkhead box protein O3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.41 / 1. The record also includes population frequency data, published literature, and structural context.
P8L (p.Pro8Leu) variant details
- p.Pro8Leu
- gnomAD 6-108561231-C-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.405
- REVEL 0.28
- MetaLR 0.37
- MetaSVM -0.47
- CADD 23.00
- PolyPhen-2 0.00
- SIFT 0.09
- Population evidence available
- Structural context available
- Literature evidence available