P8A (p.Pro8Ala) variant of FOXO3 (Forkhead box protein O3)
P8A (p.Pro8Ala) in FOXO3 (Forkhead box protein O3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.46 / 1. The record also includes population frequency data, published literature, and structural context.
P8A (p.Pro8Ala) variant details
- p.Pro8Ala
- gnomAD 6-108561230-C-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.461
- REVEL 0.34
- MetaLR 0.44
- MetaSVM -0.31
- CADD 19.90
- PolyPhen-2 0.01
- SIFT 0.06
- Population evidence available
- Structural context available
- Literature evidence available