P5T (p.Pro5Thr) variant of FOXO3 (Forkhead box protein O3)
P5T (p.Pro5Thr) in FOXO3 (Forkhead box protein O3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.26 / 1. The record also includes population frequency data, published literature, and structural context.
P5T (p.Pro5Thr) variant details
- p.Pro5Thr
- gnomAD 6-108561221-C-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.264
- REVEL 0.15
- MetaLR 0.40
- MetaSVM -0.50
- CADD 15.80
- PolyPhen-2 0.01
- SIFT 0.10
- Population evidence available
- Structural context available
- Literature evidence available