P44T (p.Pro44Thr) variant of FOXO3 (Forkhead box protein O3)
P44T (p.Pro44Thr) in FOXO3 (Forkhead box protein O3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.39 / 1. The record also includes population frequency data, published literature, and structural context.
P44T (p.Pro44Thr) variant details
- p.Pro44Thr
- gnomAD 6-108561338-C-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.385
- REVEL 0.27
- MetaLR 0.43
- MetaSVM -0.13
- CADD 17.20
- PolyPhen-2 0.02
- SIFT 0.31
- Most common in the Non-Finnish European population (allele frequency 9.2e-07)
- Structural context available
- Literature evidence available