P44S (p.Pro44Ser) variant of FOXO3 (Forkhead box protein O3)
P44S (p.Pro44Ser) in FOXO3 (Forkhead box protein O3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.36 / 1. The record also includes population frequency data and structural context.
P44S (p.Pro44Ser) variant details
- p.Pro44Ser
- Ensembl rs917692418
- Missense
- Variant Prioritization Score for Impact Estimate 0.36
- REVEL 0.21
- MetaLR 0.44
- MetaSVM -0.27
- CADD 16.90
- PolyPhen-2 0.01
- SIFT 0.59
- Most common in the Non-Finnish European population (allele frequency 9.2e-07)
- Structural context available