P38R (p.Pro38Arg) variant of FOXO3 (Forkhead box protein O3)
P38R (p.Pro38Arg) in FOXO3 (Forkhead box protein O3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.52 / 1. The record also includes population frequency data and structural context.
P38R (p.Pro38Arg) variant details
- p.Pro38Arg
- ExAC rs775459697
- TOPMed rs775459697
- gnomAD rs775459697
- Missense
- Variant Prioritization Score for Impact Estimate 0.517
- REVEL 0.42
- MetaLR 0.55
- MetaSVM -0.04
- CADD 23.20
- PolyPhen-2 0.00
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 1.5e-05)
- Structural context available