P34S (p.Pro34Ser) variant of FOXO3 (Forkhead box protein O3)
P34S (p.Pro34Ser) in FOXO3 (Forkhead box protein O3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.70 / 1. The record also includes population frequency data and structural context.
P34S (p.Pro34Ser) variant details
- p.Pro34Ser
- TOPMed rs1775776958
- Missense
- Variant Prioritization Score for Impact Estimate 0.705
- REVEL 0.64
- MetaLR 0.93
- MetaSVM 1.21
- CADD 23.50
- PolyPhen-2 0.14
- SIFT 0.00
- Most common in the Latino/Admixed American population (allele frequency 6.5e-05)
- Structural context available