P28T (p.Pro28Thr) variant of FOXO3 (Forkhead box protein O3)
P28T (p.Pro28Thr) in FOXO3 (Forkhead box protein O3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.59 / 1. The record also includes population frequency data, published literature, and structural context.
P28T (p.Pro28Thr) variant details
- p.Pro28Thr
- gnomAD 6-108561290-C-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.591
- REVEL 0.51
- MetaLR 0.63
- MetaSVM 0.44
- CADD 23.10
- PolyPhen-2 0.19
- SIFT 0.00
- Population evidence available
- Structural context available
- Literature evidence available