P28L (p.Pro28Leu) variant of FOXO3 (Forkhead box protein O3)
P28L (p.Pro28Leu) in FOXO3 (Forkhead box protein O3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.54 / 1. The record also includes population frequency data, published literature, and structural context.
P28L (p.Pro28Leu) variant details
- p.Pro28Leu
- gnomAD 6-108561291-C-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.544
- REVEL 0.45
- MetaLR 0.58
- MetaSVM 0.22
- CADD 23.60
- PolyPhen-2 0.00
- SIFT 0.00
- Population evidence available
- Structural context available
- Literature evidence available