P24T (p.Pro24Thr) variant of FOXO3 (Forkhead box protein O3)
P24T (p.Pro24Thr) in FOXO3 (Forkhead box protein O3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.79 / 1. The record also includes population frequency data, published literature, and structural context.
P24T (p.Pro24Thr) variant details
- p.Pro24Thr
- gnomAD 6-108561278-C-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.793
- REVEL 0.78
- MetaLR 0.98
- MetaSVM 1.07
- CADD 25.00
- PolyPhen-2 0.99
- SIFT 0.00
- Population evidence available
- Structural context available
- Literature evidence available