P20Q (p.Pro20Gln) variant of FOXO3 (Forkhead box protein O3)
P20Q (p.Pro20Gln) in FOXO3 (Forkhead box protein O3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.74 / 1. The record also includes population frequency data, published literature, and structural context.
P20Q (p.Pro20Gln) variant details
- p.Pro20Gln
- gnomAD 6-108561267-C-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.736
- REVEL 0.73
- MetaLR 0.74
- MetaSVM 0.62
- CADD 26.00
- PolyPhen-2 0.66
- SIFT 0.01
- Population evidence available
- Structural context available
- Literature evidence available