P13R (p.Pro13Arg) variant of FOXO3 (Forkhead box protein O3)
P13R (p.Pro13Arg) in FOXO3 (Forkhead box protein O3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.42 / 1. The record also includes population frequency data, published literature, and structural context.
P13R (p.Pro13Arg) variant details
- p.Pro13Arg
- gnomAD 6-108561246-C-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.424
- REVEL 0.26
- MetaLR 0.42
- MetaSVM -0.38
- CADD 20.40
- PolyPhen-2 0.00
- SIFT 0.03
- Most common in the Non-Finnish European population (allele frequency 9.2e-07)
- Structural context available
- Literature evidence available