P10S (p.Pro10Ser) variant of FOXO3 (Forkhead box protein O3)
P10S (p.Pro10Ser) in FOXO3 (Forkhead box protein O3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.36 / 1. The record also includes population frequency data and structural context.
P10S (p.Pro10Ser) variant details
- p.Pro10Ser
- TOPMed rs1298438711
- gnomAD rs1298438711
- Missense
- Variant Prioritization Score for Impact Estimate 0.361
- REVEL 0.24
- MetaLR 0.45
- MetaSVM -0.17
- CADD 19.80
- PolyPhen-2 0.00
- SIFT 0.13
- Most common in the East Asian population (allele frequency 0.00019)
- Structural context available