P10A (p.Pro10Ala) variant of FOXO3 (Forkhead box protein O3)
P10A (p.Pro10Ala) in FOXO3 (Forkhead box protein O3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.32 / 1. The record also includes population frequency data and structural context.
P10A (p.Pro10Ala) variant details
- p.Pro10Ala
- TOPMed rs1298438711
- gnomAD rs1298438711
- Missense
- Variant Prioritization Score for Impact Estimate 0.316
- REVEL 0.18
- MetaLR 0.34
- MetaSVM -0.49
- CADD 18.10
- PolyPhen-2 0.00
- SIFT 0.12
- Most common in the Finnish in Finland (FIN) population (allele frequency 9.4e-05)
- Structural context available