L18P (p.Leu18Pro) variant of FOXO3 (Forkhead box protein O3)
L18P (p.Leu18Pro) in FOXO3 (Forkhead box protein O3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.51 / 1. The record also includes population frequency data, published literature, and structural context.
L18P (p.Leu18Pro) variant details
- p.Leu18Pro
- gnomAD 6-108561261-T-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.511
- REVEL 0.51
- MetaLR 0.42
- MetaSVM -0.37
- CADD 23.80
- PolyPhen-2 0.00
- SIFT 0.00
- Population evidence available
- Structural context available
- Literature evidence available