L18L (p.Leu18Leu) variant of FOXO3 (Forkhead box protein O3)
L18L (p.Leu18Leu) in FOXO3 (Forkhead box protein O3) is a synonymous change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.46 / 1. The record also includes population frequency data, published literature, and structural context.
L18L (p.Leu18Leu) variant details
- p.Leu18Leu
- gnomAD 6-108561260-C-T
- Synonymous
- Variant Prioritization Score for Impact Estimate 0.459
- CADD 12.80
- Most common in the Non-Finnish European population (allele frequency 9.2e-07)
- Structural context available
- Literature evidence available