L14P (p.Leu14Pro) variant of FOXO3 (Forkhead box protein O3)
L14P (p.Leu14Pro) in FOXO3 (Forkhead box protein O3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.46 / 1. The record also includes population frequency data and structural context.
L14P (p.Leu14Pro) variant details
- p.Leu14Pro
- gnomAD rs1775775411
- Missense
- Variant Prioritization Score for Impact Estimate 0.458
- REVEL 0.41
- MetaLR 0.40
- MetaSVM -0.42
- CADD 22.00
- SIFT 0.07
- Most common in the Non-Finnish European population (allele frequency 1.5e-05)
- Structural context available