L11I (p.Leu11Ile) variant of FOXO3 (Forkhead box protein O3)
L11I (p.Leu11Ile) in FOXO3 (Forkhead box protein O3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.33 / 1. The record also includes population frequency data, published literature, and structural context.
L11I (p.Leu11Ile) variant details
- p.Leu11Ile
- gnomAD 6-108561239-C-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.333
- REVEL 0.26
- MetaLR 0.35
- MetaSVM -0.62
- CADD 16.50
- PolyPhen-2 0.09
- SIFT 0.13
- Population evidence available
- Structural context available
- Literature evidence available