E3V (p.Glu3Val) variant of FOXO3 (Forkhead box protein O3)
E3V (p.Glu3Val) in FOXO3 (Forkhead box protein O3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.50 / 1. The record also includes population frequency data, published literature, and structural context.
E3V (p.Glu3Val) variant details
- p.Glu3Val
- gnomAD 6-108561216-A-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.497
- REVEL 0.45
- MetaLR 0.56
- MetaSVM 0.13
- CADD 24.10
- PolyPhen-2 0.07
- SIFT 0.05
- Population evidence available
- Structural context available
- Literature evidence available