E39V (p.Glu39Val) variant of FOXO3 (Forkhead box protein O3)
E39V (p.Glu39Val) in FOXO3 (Forkhead box protein O3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.48 / 1. The record also includes population frequency data, published literature, and structural context.
E39V (p.Glu39Val) variant details
- p.Glu39Val
- gnomAD 6-108561324-A-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.481
- REVEL 0.42
- MetaLR 0.55
- MetaSVM 0.09
- CADD 23.80
- PolyPhen-2 0.13
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 9.2e-07)
- Structural context available
- Literature evidence available